Authors : R. A. Markandewar, S. R. Deshmukh and M. A. Baseer
Page Nos : 1-6
Description :
Abstract:
Piperazines and their analogs are amongst the most important backbones in today’s drug discovery industries. The purpose of this paper is to provide an overview of the pharmacological properties of piperazines and Reaction dynamics. The synthesis of of 4-(4-methyl piperazine-l-yl) benzaldehyde a variety of Nitrogen containing aldehyde is described
with proper choice of base, solvent and temperature conditions. This work is underway to ameliorate difficulties which remain, especially in finding suitable reaction dynamics that efficiently increases the yield. . The synthesized compounds were characterized by IR,
1HNMR and MS Spectroscopy.
Keywords: Piperazines Nitrogen-containing-aldehyde, Reaction dynamics, N-arylation .
