Authors : B. P. Khobragade1, P.T.Kosankar2, S.E.Bhandarkar
Page Nos : 620-628
Description :
2-Acetyl- 4-substituted-1-naphthol have been synthesized from 4-substituted-1-
naphthol by refluxing 4-substituted-1-naphthol with glacial acetic acid in presence of
fused ZnCl2. Chalcones were synthesized from from 2-acetyl-4-substituted -1-naphthol
by condensing it with aromatic aldehydes. Then these chalcones were cyclized with
urea/thiourea in the presence of alcoholic KOH to give titled oxazins/thiazins. The
synthesized compounds were characterized by elemental analysis, 1H NMR, IR
Spectroscopy. All Newly synthesized compound were scanned for their antimicrobial
and antifungal activity and all newly synthesized compounds shows an excellent
antimicrobial and antifungal activities.
