Authors : S T. Bhandakkar and D.P. Gogle
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Description :
This research was conducted with the aim of examining the antibacterial and antifungal properties of Roots of Cadaba fruticosa (L. ) Druce. Additionally, it aimed to assess the zone of inhibition of extracts on specific bacterial and fungal strains. In this study, the microbial efficacy of Dimethyl Sulfoxide extracts of Root of Cadaba fruticosa (L. ) Druce was assessed for possible antimicrobial properties against clinically relevant bacterial and fungal strains. The antimicrobial efficacy was evaluated in the extracts using the Agar disc diffusion techn ique (Kirby-Bauer method). The antibacterial and antifungal effects of extracts (62. 5,125,250,500, 1000 μg/ml) of Cadaba fruticosa (L. ) Druce were assessed against two Gram-positive—Bacillus subtilis, Staphylococcus aureus; two Gram-negative—Escherichia coli, Pseudomonas aeruginosa human pathogenic bacteria; and two fungal strains—Candida tropicalis and Trichoderma asperellum. Zones of inhibition of extracts were compared with that of standards such as Ciprofloxacin for antibacterial effectiveness and Amphotericin B for antifungal effectiveness. The findings indicated that the extract exhibits weak to moderate antibacterial and No antifungal activity against the tested organisms.
