Authors : A K. Kawadkar., D. R. Saxena., N. J. Tupkar., S. P. Deotare
Page Nos : 36-40
Description :
The enzyme alkaline phosphatase is a hydrolytic enzyme that is enzyme elaborated by a combined efforts of the GERL complex in cells of reproductive organs of animals and humans under the influence of sex-hormones (testosterone, estrogen). This enzyme shows periodical fluctuations according to the various stages of the reproductive cycle, especially the copulatory cycle when it is secreted on higher quantity coinciding with the first active breeding period (Oct-Nov) when its value is nearly twice to that recorded at the second active breeding period (Feb-March) in the bat, Cynopterus sphinx (vahl) a fruit consuming bat that is widely distributed in Indian subcontinent. During prebreeding season (Aug- Sep) the synthesis and secretion starts elevating, and in post- breeding season it starts declining to reach a level that is low and matches with the absence of spermatogenesis in the testes. The accessory sex organs follow the above trend in production of this enzyme during other phases the reproductive cycle. Alkaline phosphatase is absent in nonsecretory tissues, their presence in sex-organs have been linked to transport of sugar across the cells, thereby helping in secretory processes, maintenance of functional inter-relationship between these organs. The enzyme is androgen dependent in the testes and accessory sex organs. One can hypothesize presence of genes in the gonadotrophs present in pituitary gland as well as in testes interstitial and germinal cells, if not in sex- organs. A feedback mechanism may be regulating formation of more lysosome populations of hydrolytic organelles during the entire reproductive cycle of this bat for modelling of cells as well as digesting the residual unwanted structures to be reused again to commence a new mitotic – meiotic turn – over cycles again to help successful continuation of and existence of the species.
