Authors : P. H. Kumbhare
Page Nos : 22-26
Description :
The virulent strains of Staphylococci and Streptococci commonly cause skin infections in human. Virulent Staphylococcus aureus usually cause nosocomial infections such as Boils, Post-operative sepsis, Septicemia, Abscess etc. Previously most of the virulent strains of S. aureus were found be susceptible to Penicillin antibiotic. However, in late 1980s, about 50% strains of S. aureus were emerged as Penicillin resistant. In late 1980s Methicillin was applied to treat Staphylococcal infections. However, within 10-15 years, 50 % isolates became resistant to Methicillin and resulted endemics in hospitals worldwide. In late 1980s, about 50% strains of S. aureus were emerged as Methicillin resistant. In early 1990s the use of a Glycopeptide antibiotic, ‘Vancomycin’ started against Penicillin resistant strain of S. aureus. Increase in the use of Vancomycin again resulted in to the emergence of Vancomycin resistant S. aureus in late 1990s. With reference to the above facts, the present review study was carried out to isolate, identify and screen out the Vancomycin antibiotic resistant S. aureus isolates from clinical specimens such as blood, pus, abscess, wound and carbuncle etc., collected from the patients in hospitals in Ballarpur City area. The screening of Vancomycin resistant S. aureus was made by a standard Baur-Kirby method. Out of 50 clinical specimen isolates analyzed about 40 % pathogenic S. aureus isolates were found to be resistant to Vancomycin antibiotic.
