Authors : S.S.Nimgare and V.P.Telkhade
Page Nos : 296-298
Description :
Obesity is defined as Body Mass Index (BMI) of >30Kg/m2.Obesity has reduced life expectancy. It is now recognized that obesity exerts an adverse effect on pregnancy. Obese women have more infertility and are less successful at conceiving than woman of normal weight. Obesity decreases successful pregnancy rates in both natural and assisted conception cycles.
The mechanism by which obesity reduces pregnancy rates are complex and multifactorial. Insulin resistance appears to be a key factor of obesity. It decreases ovulation rates and increase biochemical abnormalities. Insulin resistance also causes Polycystic Ovarian Syndrome. Adipose tissue has been shown to disturb sex hormones secretion and bioavailability. Some psychological and and socio-biological factors are also responsible for reduced fertility in obese women.
