Authors : D. B. Jadhao
Page Nos : 257-260
Description :
Abstract:
The isomeric transformation of 2-tetra-O- acetyl -β – D –glucopyransylamino-4- phynyl -5- aryl/alkylimino1,3,4-thiadiazoline have been investigated in 5% aqueous sodium carbonate solution under two conditions . When the transformation was tried with heating duration of 60 min.,2- phenyl 3- aryl /akylimino-4-tetra-O-acetyl- β -D-glucopyranosyl-5-mercapto-1,2,4-triazolines have been isolated almost exclusively. While increasing the heating time to 6-8 h., a mixture of two products , (i) 2-phenyl-3-aryl/alkylimino 4-tetra –O- acetyl- β -D glucopyranosyl 1-5-hydroxy(enolic)-1,2,4-triazolines (major) and (ii) 2-phenyl-3-aryl/alkylimino 4-tetra-O-acetyl- β -D- glucopyranosyl-5-mercapto-1,2,4- triazolines (minor) have been isolated. The structural assignments have been made on the basis of certain chemical transformations and UV, IR, NMR, mass spectral analysis.
