Authors : V. A. Fulzele and A. A. Fulzele
Page Nos : 417-423
Description :
The matrix protein of negative stranded RNA virus plays an important role in assembly and budding. The matrix protein of Ebola virus VP40 is involved in formation and release of filamentous Ebola virus like particles (VLP).The interaction and evolution of VP40 of Ebola virus could play an important step in studying the virus. In present study, VP40 matrix protein was computationally analyzed for its domain, evolutionary relationship and interaction with host protein tubulin. Here we carried out docking process of VP40 matrix protein of Ebola virus with host alpha tubulin using HEX docking software. Depending upon the docking energy values, we have chosen the best interacting structure (-890.36).
