Authors : Patil S. D., Jane R. R., Puri V. S. and Ukesh C. S.
Page Nos : 139-144
Description :
Acetone, methanol and chloroform extracts obtained from Cleome viscosa and Cardiospermum halicacabum were evaluated for their in vitro antifungal activity. The activity was tested against human pathogenic clinical isolates of filamentous fungi associated with otitis media by disc diffusion method. Cleome viscosa and Cardiospermum halicacabum extracts displayed highest antifungal activity with 12 and 13 mm inhibition zone respectively. Methanol extracts of Cleome viscosa and Cardiospermum halicacabum were able to inhibit 78 and 72% fungal isolates respectively while the standard antifungal agent fluconazole exhibited extremely poor antifungal activity. The results suggest the possible use of the above plants for the treatment of ear infections due to fungi.
