Special Issue Description


Authors : Prakash Itankar , Ashlesh Murkute.

Page Nos : 68-74

Description :
This work aims to determine the in-vitroanti-cancer activity of biotransformed material (extract) of Embellica officinalis fruits. Various concentrations of the biotransformed material (extract) of Embellica officinalis were tested. The MTT assay method was used using A549 cell lines, LN Cap-FGC cell linesand MDA-MB cell lines. The result shows promising effect of biotransformed material (extract) of Embellica officinalis. The IC50 values were found to be less than10 µg against A549 cell lines, the activities against LN Cap-FGC cell lines were found to be 10 µg and IC 50 values were found to be 10 µg against MDA-MB cell lines From this study it was evident that the cancer cell growth was significantly inhibited by treatment with biotransformed material (extract). Hence, in vitro studies of Embellica officinalis was found to have a potential anti-cancer activity.

Date of Online: 30 Special Issue-1, Dec. 2014