Authors : Vijendra Batra, Vijay H. Masand, A. A. Nerkar and D. T. Mahajan
Page Nos : 480-481
Description :
Chagas disease affects millions of peoples each year. In present study, we have determined pharmacophoric site and pattern which governs the anti-chagas activity of Heterocyclic-2-Carboxylic Acid (3-Cyano-1,4-di-Noxidequinoxalin-2-yl)amide Derivatives. The study using POM reveals that presence of charges due to N-H and –CN group affects the activity.
