Authors : Shipra Bodele, Virendra G. Meshram and Utpal J. Dongre
Page Nos : 162-165
Description :
The present study was attempted to estimate the level of antioxidant enzymes, free radicals and Mitochondrial DNA 3243 A/G mutation in patients of MELAS syndrome. All standard methods were used to evaluate oxidative stress and mitochondrial DNA mutation. There was alteration in the level of antioxidant enzymes and no mutation was observed. Although there was alteration in the activities of antioxidant enzymes, no mutation was detected in the mitochondrial DNA.
Keywords: Oxidative stress, Antioxidant enzymes, Free radicals, Mitochondrial DNA.
