Authors : P. Sampada, G. Kavita, M. Renuka
Page Nos : 35-42
Description :
A new series of thiazolidinone derivatives (6a-c) were synthesized by the reaction of Schiff base(4a-c) with mercaptoacetic acid respectively. The chemical structure of the synthesized compounds were confirmed organic qualitative analysis and then anti-microbial activity was carried out. The different synthesis thiazolidinone derivatives from Benzyloxy benzaldehyde showed good anti bacterial activity against both gram positive and gram negative such as Staphylococcus auresus, S.typhi, Erwinia, X.Oxalopodi and Eischerchia coli. In this when compare to compound I, Compound II showed more inhibition. The average area of inhibition in millimeter (mm) was calculated and compared with that of the standard chloramphenicol.
