Authors : S. Satpute, D. Panhekar and A. Kalambe
Page Nos : 368-372
Description :
Abstract:
Chromenes are heterocyclic molecules of considerable interest because of the diverse range of their biological properties. A series of 3-hydroxy-2-(substituted) phenyl-4H-chromene-4-one were synthesized in microwave oven and by conventional method. Derivatives of 3-hydroxy-2-(substituted)phenyl-4H-chromene-4-one were synthesized from 2’-hydroxychalcones using hydrogen peroxide and sodium hydroxide. Their chemical transformations by conventional method took hours for reaction completion whereas reactions under microwave irradiation resulted in drastic reduction of time along with improved yield of the product.
Keywords: chromene, microwave irradiation, hydrogen peroxide.
