Authors : P. Katolkar, S. Bhuskute and N. Duragkar
Page Nos : 232-236
Description :
Abstract:
The present study was designed to evaluate the antianxiety and antidepressant activity of the ethanolic and aqueous extracts of Cestrum nocturnum leaves in rodents. Antianxiety activity was tested by exposing rats to unfamiliar aversion in different methods like elevated plus maze model and actophotometer. The results infer that reduced aversion fear elicits antianxiety activity. The antidepressant activity was tested by using despair swim test and tail suspension test. The results infer that reduced immobility time elicits antidepressant activity. It was concluded that ethanolic and aqueous extracts of Cestrum nocturnum leaves having antianxiety and antidepressant activity. Ethanolic extract of Cestrum nocturnum leaves showing more significant activity over the aqueous extract.
Keywords: Cestrum nocturnum, Antianxiety activity, Antidepressant activity, Elevated plus maze, Actophotometer, Despair swim test.
