Issue Description


Authors : R. A. Nalawade, A. M. Nalawade, C. P. Mane, D. V. Rupnawar, M. K. Sakate, B. S. Londhe, R. V. Shejwal and M. A. Anuse

Page Nos : 139-141

Description :
Abstract: Development of simple, efficient, environmentally begin and economically viable chemical process or methodologies for synthsis of organic compounds are in great demand. A (E) - N\' - (4-methylbenzylidene) hydrazinecarbothiohydrazide (4-methyl B) HCT has been synthesized by reacting 4-methyl benzaldehyde and thiocarbohydrazide under microwave irradiation without catalyst under solvent free condition, as a green chemistry approach. The reaction proceeds selectively within a couple of minutes giving high yields of the product. The compound was characterized by elemental, Uv-visible, IR, NMR and mass spectra. The compound was tested for the evaluation of antibacterial activity against S. aureus and E. coli and antifungal activity against A. niger and Rhizopus spe.The compound is biologically active in very low concentration Keywords: Microwave mediated synthesis, thiocarbohydrazide, green chemistry, Antibacterial and antifungal activity

Date of Online: 30 May 2015