Authors : N. P. Mohabansi, A. K. Satone, Gulafsha A. I. Sheikh, Komal Vairagade
Page Nos : 26-34
Description :
Density(ρ), Viscosity(η), Ultrasonic Velocity(U) and Surface Tension(γ) of an aqueous-consolute, Na2SO4 solution of [2-(dimethylamino)-1-(4-methoxyphenyl) ethyl] cyclohexan-1-ol (Venlafaxine) 0.0201,0.0402,0.0804,0.1608 mol/kg were measured at 293.15, 303.15 and 313.15K. The resulting data were used to calculate various acoustical parameters, acoustic impedance (Z), adiabatic compressibility(β), Intermolecular free length (Lf), Wada’s Constant (W), Rao’s Constant (R), free volume (Vf), Relative Association (RA) were calculated which provides valuable information regarding drug-electrolyte (Na2SO4) interaction. The excess parameters viz. partial molar volume and excess adiabatic compressibility (βE), excess inter molecular free length (LfE), excess free volume (VfE) were also calculated. These calculations help in predicting the intermolecular interactions.
