Authors : Archana Kulkarni
Page Nos : 69-75
Description :
Methicillin resistant Staphylococcus aureus (MRSA) infections are posing threat to the community. They have high rate of mortality and requires longer hospital stays than do other S.aureus infections. To overcome this problem the use of volatile oils presents a more directly antimicrobial approach to MRSA infections. The essential oils of cinnamon
and clove have antibacterial, antifungal, and anti-inflammatory properties. Here in this article anti Staphylococcal effect of cinnamon and clove oils nanoemulsions to combat MRSA were studied by using Tween 20(T20) and Tween 80(T80) separately in the ratio of 1:1(oil to surfactant ratio), 1:2, 1:3,1:4. As reported earlier, since the droplet size
of nanoemulsions of oils has direct role in deciding antibacterial activity, the droplet size and polydispersity index(pdi) studies were undertaken. Eight nanoemulsions were tested using agar well diffusion method out of which maximum antibacterial activity was exhibited by Cinnamon oil nanoemulsions formulation i.e. 80C 4 (1:4 oil to T80 ratio) with
mean value of ZOI as 35.07 mm, followed by 20C4 (1:4 oil to T20 ratio) of 33.68 mm, having droplet size of 133.6nm and 272.3nm respectively. Clove oil was found to show less activity with the maximum mean ZOI value as 16.23mm for 20Cl2(1:2 oil to T20ratio), and14.27mm for 80Cl1(1:1 oil to T80 ratio). Our findings suggested that cinnamon oil nanoemulsions has a potential to be a herbal antibacterial agent.
